Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression

Regulation of the actin-myosin cytoskeleton plays a central role in cell migration and cancer progression. Here, we report the discovery of a cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filame...

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Bibliografiske detaljer
Main Authors: Wang, Yingchun, Kelber, Jonathan A., Cao, Hop S. Tran, Cantin, Greg T., Lin, Rui, Wang, Wei, Kaushal, Sharmeela, Bristow, Jeanne M., Edgington, Thomas S., Hoffman, Robert M., Bouvet, Michael, Yates, John R., Klemke, Richard L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890752/
https://ncbi.nlm.nih.gov/pubmed/20534451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914776107
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