Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression

Regulation of the actin-myosin cytoskeleton plays a central role in cell migration and cancer progression. Here, we report the discovery of a cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filame...

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Detalhes bibliográficos
Main Authors: Wang, Yingchun, Kelber, Jonathan A., Cao, Hop S. Tran, Cantin, Greg T., Lin, Rui, Wang, Wei, Kaushal, Sharmeela, Bristow, Jeanne M., Edgington, Thomas S., Hoffman, Robert M., Bouvet, Michael, Yates, John R., Klemke, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890752/
https://ncbi.nlm.nih.gov/pubmed/20534451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914776107
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