Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression

Regulation of the actin-myosin cytoskeleton plays a central role in cell migration and cancer progression. Here, we report the discovery of a cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filame...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yingchun, Kelber, Jonathan A., Cao, Hop S. Tran, Cantin, Greg T., Lin, Rui, Wang, Wei, Kaushal, Sharmeela, Bristow, Jeanne M., Edgington, Thomas S., Hoffman, Robert M., Bouvet, Michael, Yates, John R., Klemke, Richard L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890752/
https://ncbi.nlm.nih.gov/pubmed/20534451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914776107
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