Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription

PEAK1 is a newly described tyrosine kinase and scaffold protein that transmits integrin-mediated extracellular matrix (ECM) signals to facilitate cell movement and growth. While aberrant expression of PEAK1 has been linked to cancer progression, its normal physiological role in vertebrate biology is...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Wang, Huawei, Lapek, John, Fujimura, Ken, Strnadel, Jan, Liu, Bei, Gonzalez, David J., Zhang, Wei, Watson, Felicia, Yu, Vicky, Liu, Chao, Melo, Carina Muccilo, Miller, Yury I., Elliott, Kathryn C., Cheresh, David A., Klemke, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972149/
https://ncbi.nlm.nih.gov/pubmed/29872538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0024-3
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