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VEGFR3 does not sustain retinal angiogenesis without VEGFR2

Angiogenesis, the formation of new blood vessels, is regulated by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). VEGFR2 is abundant in the tip cells of angiogenic sprouts, where VEGF/VEGFR2 functions upstream of the delta-like ligand 4 (DLL4)/Notch signal transduction path...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zarkada, Georgia, Heinolainen, Krista, Makinen, Taija, Kubota, Yoshiaki, Alitalo, Kari
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311859/
https://ncbi.nlm.nih.gov/pubmed/25561555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423278112
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