The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

In glaucoma, aqueous outflow into the Schlemm’s canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell marker...

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Detalhes bibliográficos
Principais autores: Aspelund, Aleksanteri, Tammela, Tuomas, Antila, Salli, Nurmi, Harri, Leppänen, Veli-Matti, Zarkada, Georgia, Stanczuk, Lukas, Francois, Mathias, Mäkinen, Taija, Saharinen, Pipsa, Immonen, Ilkka, Alitalo, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153703/
https://ncbi.nlm.nih.gov/pubmed/25061878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75395
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