The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

In glaucoma, aqueous outflow into the Schlemm’s canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell marker...

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Autori principali: Aspelund, Aleksanteri, Tammela, Tuomas, Antila, Salli, Nurmi, Harri, Leppänen, Veli-Matti, Zarkada, Georgia, Stanczuk, Lukas, Francois, Mathias, Mäkinen, Taija, Saharinen, Pipsa, Immonen, Ilkka, Alitalo, Kari
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153703/
https://ncbi.nlm.nih.gov/pubmed/25061878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75395
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