The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

In glaucoma, aqueous outflow into the Schlemm’s canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell marker...

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Autores principales: Aspelund, Aleksanteri, Tammela, Tuomas, Antila, Salli, Nurmi, Harri, Leppänen, Veli-Matti, Zarkada, Georgia, Stanczuk, Lukas, Francois, Mathias, Mäkinen, Taija, Saharinen, Pipsa, Immonen, Ilkka, Alitalo, Kari
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153703/
https://ncbi.nlm.nih.gov/pubmed/25061878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75395
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