The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

In glaucoma, aqueous outflow into the Schlemm’s canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell marker...

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Bibliographische Detailangaben
Hauptverfasser: Aspelund, Aleksanteri, Tammela, Tuomas, Antila, Salli, Nurmi, Harri, Leppänen, Veli-Matti, Zarkada, Georgia, Stanczuk, Lukas, Francois, Mathias, Mäkinen, Taija, Saharinen, Pipsa, Immonen, Ilkka, Alitalo, Kari
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153703/
https://ncbi.nlm.nih.gov/pubmed/25061878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75395
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