The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

In glaucoma, aqueous outflow into the Schlemm’s canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell marker...

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Hlavní autoři: Aspelund, Aleksanteri, Tammela, Tuomas, Antila, Salli, Nurmi, Harri, Leppänen, Veli-Matti, Zarkada, Georgia, Stanczuk, Lukas, Francois, Mathias, Mäkinen, Taija, Saharinen, Pipsa, Immonen, Ilkka, Alitalo, Kari
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153703/
https://ncbi.nlm.nih.gov/pubmed/25061878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75395
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