Lysine Methylation Promotes VEGFR-2 Activation and Angiogenesis

Activation of vascular endothelial growth factor receptor-2 (VEGFR-2), an endothelial cell receptor tyrosine kinase, promotes tumor angiogenesis and ocular neovascularization. We report the methylation of VEGFR-2 at multiple Lys and Arg residues, including Lys(1041), a residue that is proximal to th...

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Detalhes bibliográficos
Main Authors: Hartsough, Edward J., Meyer, Rosana D., Chitalia, Vipul, Jiang, Yan, Marquez, Victor E., Zhdanova, Irina V., Weinberg, Janice, Costello, Catherine E., Rahimi, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108444/
https://ncbi.nlm.nih.gov/pubmed/24300896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004289
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