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RNF121 inhibits angiogenic growth factor signaling by restricting cell surface expression of VEGFR-2
Ligand stimulation promotes downregulation of RTKs, a mechanism by which RTKs, through the ubiquitination pathway are removed from the cell surface, causing a temporary termination of RTK signaling. The molecular mechanisms governing RTK trafficking and maturation in the endoplasmic reticulum (ER)/G...
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| Publicado no: | Traffic |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767591/ https://ncbi.nlm.nih.gov/pubmed/26602861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12353 |
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