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The Carboxyl Terminus Controls Ligand-dependent Activation of VEGFR-2 and Its Signaling

Vascular endothelial growth factor receptor-2 (VEGFR-2/FLK-1) is a receptor tyrosine kinase whose activation stimulates angiogenesis. We recently generated a chimeric VEGFR-2 in which the extracellular domain of VEGFR-2 was replaced with the extracellular domain of human colony stimulating factor-1...

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Autori principali: Meyer, Rosana D., Singh, Amrik J., Rahimi, Nader
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464116/
https://ncbi.nlm.nih.gov/pubmed/14573614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M305575200
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