N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2)

The tumor microenvironment and proinflammatory signals significantly alter glycosylation of cell-surface proteins on endothelial cells. By altering the N-glycosylation machinery in the endoplasmic reticulum and Golgi, proinflammatory cytokines promote the modification of endothelial glycoproteins su...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Chandler, Kevin Brown, Leon, Deborah R., Kuang, Jenevieve, Meyer, Rosana D., Rahimi, Nader, Costello, Catherine E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721943/
https://ncbi.nlm.nih.gov/pubmed/31308178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008643
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