Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression

Regulation of the actin-myosin cytoskeleton plays a central role in cell migration and cancer progression. Here, we report the discovery of a cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filame...

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Détails bibliographiques
Auteurs principaux: Wang, Yingchun, Kelber, Jonathan A., Cao, Hop S. Tran, Cantin, Greg T., Lin, Rui, Wang, Wei, Kaushal, Sharmeela, Bristow, Jeanne M., Edgington, Thomas S., Hoffman, Robert M., Bouvet, Michael, Yates, John R., Klemke, Richard L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890752/
https://ncbi.nlm.nih.gov/pubmed/20534451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914776107
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