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Fluorophilicity of Alkyl and Polyfluoroalkyl 1 Nicotinic Acid Ester Prodrugs

The fluorophilicity of a series of hydrocarbon and fluorocarbon-functionalized nicotinic acid esters (nicotinates) is measured from their partitioning behavior (log K(P)) in the biphasic solvent system of perfluoro(methylcyclohexane) (PFMC) and toluene. The chain length of the hydrocarbon or fluoroc...

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Bibliografiske detaljer
Main Authors: Ojogun, Vivian, Knutson, Barbara L, Vyas, Sandhya, Lehmler, Hans-Joachim
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887708/
https://ncbi.nlm.nih.gov/pubmed/20567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2010.04.001
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