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Partitioning of Homologous Nicotinic Acid Ester Prodrugs (Nicotinates) into Dipalmitoylphosphatidylcholine (DPPC) Membrane Bilayers

The partitioning behavior of a series of perhydrocarbon nicotinic acid esters (nicotinates) between aqueous solution and dipalmitoylphosphatidylcholine (DPPC) membrane bilayers is investigated as a function of increasing alkyl chain length. The hydrocarbon nicotinates represent putative prodrugs, de...

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Detalhes bibliográficos
Main Authors: Ojogun, Vivian, Vyas, Sandhya M., Lehmler, Hans-Joachim, Knutson, Barbara L
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873030/
https://ncbi.nlm.nih.gov/pubmed/20227859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2010.02.015
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