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Fluorophilicity of Alkyl and Polyfluoroalkyl 1 Nicotinic Acid Ester Prodrugs

The fluorophilicity of a series of hydrocarbon and fluorocarbon-functionalized nicotinic acid esters (nicotinates) is measured from their partitioning behavior (log K(P)) in the biphasic solvent system of perfluoro(methylcyclohexane) (PFMC) and toluene. The chain length of the hydrocarbon or fluoroc...

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Detalhes bibliográficos
Main Authors: Ojogun, Vivian, Knutson, Barbara L, Vyas, Sandhya, Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887708/
https://ncbi.nlm.nih.gov/pubmed/20567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2010.04.001
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