Loading...
Kinetics and Mechanisms of Activation of α-Amino Acid Ester Prodrugs of Camptothecins
The α-amino acid ester prodrugs of the antitumor agent camptothecin and a more potent, lipophilic silatecan analog, DB-67, have been shown by NMR spectroscopy and quantitative kinetic analyses to undergo quantitative conversion to their pharmacologically active lactones via a non-enzymatic mechanism...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516925/ https://ncbi.nlm.nih.gov/pubmed/16821794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060016l |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|