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Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs
Thiazolides are polypharmacology agents with at least three mechanisms of action against a broad spectrum of parasites, bacteria and viruses. In respiratory viruses they inhibit the replication of orthomyxoviridae and paramyxoviridae at a post-translational level. Nitazoxanide 1a, the prototype thia...
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| Publicado no: | Eur J Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Masson SAS.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125651/ https://ncbi.nlm.nih.gov/pubmed/27750149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.09.080 |
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