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Fluorophilicity of Alkyl and Polyfluoroalkyl 1 Nicotinic Acid Ester Prodrugs

The fluorophilicity of a series of hydrocarbon and fluorocarbon-functionalized nicotinic acid esters (nicotinates) is measured from their partitioning behavior (log K(P)) in the biphasic solvent system of perfluoro(methylcyclohexane) (PFMC) and toluene. The chain length of the hydrocarbon or fluoroc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ojogun, Vivian, Knutson, Barbara L, Vyas, Sandhya, Lehmler, Hans-Joachim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887708/
https://ncbi.nlm.nih.gov/pubmed/20567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2010.04.001
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