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Fluorophilicity of Alkyl and Polyfluoroalkyl 1 Nicotinic Acid Ester Prodrugs

The fluorophilicity of a series of hydrocarbon and fluorocarbon-functionalized nicotinic acid esters (nicotinates) is measured from their partitioning behavior (log K(P)) in the biphasic solvent system of perfluoro(methylcyclohexane) (PFMC) and toluene. The chain length of the hydrocarbon or fluoroc...

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書誌詳細
主要な著者: Ojogun, Vivian, Knutson, Barbara L, Vyas, Sandhya, Lehmler, Hans-Joachim
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887708/
https://ncbi.nlm.nih.gov/pubmed/20567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2010.04.001
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