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Fluorophilicity of Alkyl and Polyfluoroalkyl 1 Nicotinic Acid Ester Prodrugs

The fluorophilicity of a series of hydrocarbon and fluorocarbon-functionalized nicotinic acid esters (nicotinates) is measured from their partitioning behavior (log K(P)) in the biphasic solvent system of perfluoro(methylcyclohexane) (PFMC) and toluene. The chain length of the hydrocarbon or fluoroc...

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Autors principals: Ojogun, Vivian, Knutson, Barbara L, Vyas, Sandhya, Lehmler, Hans-Joachim
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887708/
https://ncbi.nlm.nih.gov/pubmed/20567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2010.04.001
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