Distinct factors control histone variant H3.3 localization at specific genomic regions

The incorporation of histone H3 variants has been implicated in the epigenetic memory of cellular state. Using genome editing with zinc finger nucleases to tag endogenous H3.3, we report genome-wide profiles of H3 variants in mammalian embryonic stem (ES) cells and neuronal precursor cells. Genome-w...

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Hauptverfasser: Goldberg, Aaron D., Banaszynski, Laura A., Noh, Kyung-Min, Lewis, Peter W., Elsaesser, Simon J., Stadler, Sonja, Dewell, Scott, Law, Martin, Guo, Xingyi, Li, Xuan, Wen, Duancheng, Chapgier, Ariane, DeKelver, Russell C., Miller, Jeffrey C., Lee, Ya-Li, Boydston, Elizabeth A., Holmes, Michael C., Gregory, Philip D., Greally, John M., Rafii, Shahin, Yang, Chingwen, Scambler, Peter J., Garrick, David, Gibbons, Richard J., Higgs, Douglas R., Cristea, Ileana M., Urnov, Fyodor D., Zheng, Deyou, Allis, C. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885838/
https://ncbi.nlm.nih.gov/pubmed/20211137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.01.003
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