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Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice
Meiotic recombination is initiated by the programmed induction of DNA double-strand breaks (DSBs) catalyzed by the evolutionarily conserved Spo11 protein. Studies in yeast have shown that DSB formation requires several other proteins, the role and conservation of which remain unknown. Here we show t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885662/ https://ncbi.nlm.nih.gov/pubmed/20551173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.571710 |
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