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Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

Meiotic recombination is initiated by the programmed induction of DNA double-strand breaks (DSBs) catalyzed by the evolutionarily conserved Spo11 protein. Studies in yeast have shown that DSB formation requires several other proteins, the role and conservation of which remain unknown. Here we show t...

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Hlavní autoři: Kumar, Rajeev, Bourbon, Henri-Marc, de Massy, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885662/
https://ncbi.nlm.nih.gov/pubmed/20551173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.571710
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