MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse

The formation of programmed DNA double-strand breaks (DSBs) at the beginning of meiotic prophase marks the initiation of meiotic recombination. Meiotic DSB formation is catalyzed by SPO11 and their repair takes place on meiotic chromosome axes. The evolutionarily conserved MEI4 protein is required f...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Kumar, Rajeev, Ghyselinck, Norbert, Ishiguro, Kei-ichiro, Watanabe, Yoshinori, Kouznetsova, Anna, Höög, Christer, Strong, Edward, Schimenti, John, Daniel, Katrin, Toth, Attila, de Massy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446737/
https://ncbi.nlm.nih.gov/pubmed/25795304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.165464
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