Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

Meiotic crossover formation involves the repair of programmed DNA double-strand breaks (DSBs) and synaptonemal complex (SC) formation. Completion of these processes must precede the meiotic divisions in order to avoid chromosome abnormalities in gametes. Enduring key questions in meiosis have been h...

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Detalhes bibliográficos
Main Authors: Wojtasz, Lukasz, Cloutier, Jeffrey M., Baumann, Marek, Daniel, Katrin, Varga, János, Fu, Jun, Anastassiadis, Konstantinos, Stewart, A. Francis, Reményi, Attila, Turner, James M.A., Tóth, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347793/
https://ncbi.nlm.nih.gov/pubmed/22549958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187559.112
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