Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

Meiotic crossover formation involves the repair of programmed DNA double-strand breaks (DSBs) and synaptonemal complex (SC) formation. Completion of these processes must precede the meiotic divisions in order to avoid chromosome abnormalities in gametes. Enduring key questions in meiosis have been h...

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Autori principali: Wojtasz, Lukasz, Cloutier, Jeffrey M., Baumann, Marek, Daniel, Katrin, Varga, János, Fu, Jun, Anastassiadis, Konstantinos, Stewart, A. Francis, Reményi, Attila, Turner, James M.A., Tóth, Attila
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347793/
https://ncbi.nlm.nih.gov/pubmed/22549958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187559.112
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