Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice

In most taxa, halving of chromosome numbers during meiosis requires that homologous chromosomes (homologues) pair and form crossovers. Crossovers emerge from the recombination-mediated repair of programmed DNA double-strand breaks (DSBs). DSBs are generated by SPO11, whose activity requires auxiliar...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Dereli, Ihsan, Stanzione, Marcello, Olmeda, Fabrizio, Papanikos, Frantzeskos, Baumann, Marek, Demir, Sevgican, Carofiglio, Fabrizia, Lange, Julian, de Massy, Bernard, Baarends, Willy M, Turner, James, Rulands, Steffen, Tóth, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969012/
https://ncbi.nlm.nih.gov/pubmed/33619545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab082
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