Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4

Programmed formation of DNA double-strand breaks (DSBs) initiates the meiotic homologous recombination pathway. This pathway is essential for proper chromosome segregation at the first meiotic division and fertility. Meiotic DSBs are catalyzed by Spo11. Several other proteins are essential for meiot...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Kumar, Rajeev, Oliver, Cecilia, Brun, Christine, Juarez-Martinez, Ariadna B, Tarabay, Yara, Kadlec, Jan, de Massy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288613/
https://ncbi.nlm.nih.gov/pubmed/30569039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800259
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