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Mechanism and Control of Meiotic DNA Double-Strand Break Formation in S. cerevisiae

Developmentally programmed formation of DNA double-strand breaks (DSBs) by Spo11 initiates a recombination mechanism that promotes synapsis and the subsequent segregation of homologous chromosomes during meiosis. Although DSBs are induced to high levels in meiosis, their formation and repair are tig...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Yadav, Vikash Kumar, Claeys Bouuaert, Corentin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968521/
https://ncbi.nlm.nih.gov/pubmed/33748134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.642737
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