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Mechanisms and Consequences of Double-strand DNA Break Formation in Chromatin
All organisms suffer double-strand breaks (DSBs) in their DNA as a result of exposure to ionizing radiation. DSBs can also form when replication forks encounter DNA lesions or repair intermediates. The processing and repair of DSBs can lead to mutations, loss of heterozygosity, and chromosome rearra...
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| Publicado no: | J Cell Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994891/ https://ncbi.nlm.nih.gov/pubmed/26040249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25048 |
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