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Model Calibration in the Continual Reassessment Method
BACKGROUND: The continual reassessment method (CRM) is an adaptive model-based design used to estimate the maximum tolerated dose in dose finding clinical trials. A way to evaluate the sensitivity of a given CRM model including the functional form of the dose-toxicity curve, the prior distribution o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884971/ https://ncbi.nlm.nih.gov/pubmed/19528132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774509105076 |
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