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Selection of the initial design for the Two-Stage Continual Reassessment Method

The continual reassessment method (CRM) was proposed in a Bayesian framework whereby the first patient is assigned to the prior guess of the maximum tolerated dose which is usually not the lowest dose level. This assignment may lead to safety concerns in practice because physicians usually prefer no...

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Detaylı Bibliyografya
Yayımlandı:J Biopharm Stat
Asıl Yazarlar: Jia, Xiaoyu, Ivanova, Anastasia, Lee, Shing M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383510/
https://ncbi.nlm.nih.gov/pubmed/28300466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1290650
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