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Calibration of prior variance in the Bayesian Continual Reassessment Method
The continual reassessment method (CRM) is an adaptive model-based design used to estimate the maximum tolerated dose in phase I clinical trials. Asymptotically, the method has been shown to select the correct dose given that certain conditions are satisfied. When sample size is small, specifying a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129459/ https://ncbi.nlm.nih.gov/pubmed/21413054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4139 |
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