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Elevated XIAP expression alone does not confer chemoresistance

BACKGROUND: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has been described and reviewed repeatedly as a chemo...

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Main Authors: Seeger, J M, Brinkmann, K, Yazdanpanah, B, Haubert, D, Pongratz, C, Coutelle, O, Krönke, M, Kashkar, H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883704/
https://ncbi.nlm.nih.gov/pubmed/20485285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605704
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