XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma–derived B Cells

The malignant Hodgkin and Reed-Sternberg cells of Hodgkin's lymphoma (HL) and HL-derived B cell lines were previously shown to be resistant to different apoptotic stimuli. We show here that cytochrome c fails to stimulate caspases-9 and -3 activation in cytosolic extracts of HL-derived B cells,...

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Huvudupphovsmän: Kashkar, Hamid, Haefs, Christiane, Shin, Hwain, Hamilton-Dutoit, Stephen J., Salvesen, Guy S., Krönke, Martin, Jürgensmeier, Juliane M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2003
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194071/
https://ncbi.nlm.nih.gov/pubmed/12874265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021279
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