Elevated XIAP expression alone does not confer chemoresistance

BACKGROUND: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has been described and reviewed repeatedly as a chemo...

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Bibliografische gegevens
Hoofdauteurs: Seeger, J M, Brinkmann, K, Yazdanpanah, B, Haubert, D, Pongratz, C, Coutelle, O, Krönke, M, Kashkar, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2010
Onderwerpen:
Translational Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883704/
https://ncbi.nlm.nih.gov/pubmed/20485285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605704
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