Elevated XIAP expression alone does not confer chemoresistance

BACKGROUND: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has been described and reviewed repeatedly as a chemo...

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Autores principales: Seeger, J M, Brinkmann, K, Yazdanpanah, B, Haubert, D, Pongratz, C, Coutelle, O, Krönke, M, Kashkar, H
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883704/
https://ncbi.nlm.nih.gov/pubmed/20485285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605704
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