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Elevated XIAP expression alone does not confer chemoresistance

BACKGROUND: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has been described and reviewed repeatedly as a chemo...

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Détails bibliographiques
Auteurs principaux: Seeger, J M, Brinkmann, K, Yazdanpanah, B, Haubert, D, Pongratz, C, Coutelle, O, Krönke, M, Kashkar, H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883704/
https://ncbi.nlm.nih.gov/pubmed/20485285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605704
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