Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD

BACKGROUND: Multidrug resistance-associated protein-1 (MRP1) protects against oxidative stress and toxic compounds generated by cigarette smoking, which is the main risk factor for chronic obstructive pulmonary disease (COPD). We have previously shown that single nucleotide polymorphisms (SNPs) in M...

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Detalhes bibliográficos
Main Authors: Budulac, Simona E, Postma, Dirkje S, Hiemstra, Pieter S, Kunz, Lisette IZ, Siedlinski, Mateusz, Smit, Henriette A, Vonk, Judith M, Rutgers, Bea, Timens, Wim, Boezen, H Marike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882908/
https://ncbi.nlm.nih.gov/pubmed/20487524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-60
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