Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD

BACKGROUND: Multidrug resistance-associated protein-1 (MRP1) protects against oxidative stress and toxic compounds generated by cigarette smoking, which is the main risk factor for chronic obstructive pulmonary disease (COPD). We have previously shown that single nucleotide polymorphisms (SNPs) in M...

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Main Authors: Budulac, Simona E, Postma, Dirkje S, Hiemstra, Pieter S, Kunz, Lisette IZ, Siedlinski, Mateusz, Smit, Henriette A, Vonk, Judith M, Rutgers, Bea, Timens, Wim, Boezen, H Marike
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882908/
https://ncbi.nlm.nih.gov/pubmed/20487524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-60
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