Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial

RATIONALE: Smoking and inflammation contribute to the pathogenesis of chronic obstructive pulmonary disease (COPD), which involves changes in extracellular matrix. This is thought to contribute to airway remodeling and airflow obstruction. We have previously observed that long-term treatment with in...

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Detalhes bibliográficos
Main Authors: Kunz, Lisette I. Z., Strebus, Jolanda, Budulac, Simona E., Lapperre, Therese S., Sterk, Peter J., Postma, Dirkje S., Mauad, Thais, Timens, Wim, Hiemstra, Pieter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646783/
https://ncbi.nlm.nih.gov/pubmed/23667615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063430
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