Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD

BACKGROUND: Macrophages have been implicated in the pathogenesis of COPD. M1 and M2 macrophages constitute subpopulations displaying pro- and anti-inflammatory properties. We hypothesized that smoking cessation affects macrophage heterogeneity in the lung of patients with COPD. Our aim was to study...

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Main Authors: Kunz, Lisette IZ, Lapperre, Thérèse S, Snoeck-Stroband, Jiska B, Budulac, Simona E, Timens, Wim, van Wijngaarden, Simone, Schrumpf, Jasmijn A, Rabe, Klaus F, Postma, Dirkje S, Sterk, Peter J, Hiemstra, Pieter S
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072953/
https://ncbi.nlm.nih.gov/pubmed/21426578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-34
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