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Nicotinic Acetylcholine Receptor Variants Are Related to Smoking Habits, but Not Directly to COPD

Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function declin...

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Main Authors: Budulac, Simona E., Vonk, Judith M., Postma, Dirkje S., Siedlinski, Mateusz, Timens, Wim, Boezen, Marike H.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305325/
https://ncbi.nlm.nih.gov/pubmed/22438921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033386
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