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Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

BACKGROUND: Cigarette smoking is the most important risk factor for Chronic Obstructive Pulmonary Disease (COPD). Only a subgroup of smokers develops COPD and it is unclear why these individuals are more susceptible to the detrimental effects of cigarette smoking. The risk to develop COPD is known t...

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Main Authors: Hoonhorst, Susan JM, Timens, Wim, Koenderman, Leo, Lo Tam Loi, Adèle T, Lammers, Jan-Willem J, Boezen, H Marike, van Oosterhout, Antoon JM, Postma, Dirkje S, ten Hacken, Nick HT
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203909/
https://ncbi.nlm.nih.gov/pubmed/25301367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0121-2
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