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Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies
Monosomy 7 and del(7q) are associated with adverse features in myeloid malignancies. A 2.5-Mb commonly deleted segment (CDS) of chromosome band 7q22 is implicated as harboring a myeloid tumor suppressor gene (TSG); however, molecular analysis of candidate TSGs has not uncovered loss of function. To...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881500/ https://ncbi.nlm.nih.gov/pubmed/20233966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-232504 |
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