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Mosaic chromosome 20q deletions are more frequent in the aging population

Deletions on the long-arm of chromosome 20, del(20q), are common karyotypic abnormalities in myeloid disorders. Bioinformatic analyses of the B-allele frequency and log R ratio values from genome-wide association data have identified individuals who are mosaic for large structural abnormalities (>...

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Machiela, Mitchell J., Zhou, Weiyin, Caporaso, Neil, Dean, Michael, Gapstur, Susan M., Goldin, Lynn, Rothman, Nathaniel, Stevens, Victoria L., Yeager, Meredith, Chanock, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738991/
https://ncbi.nlm.nih.gov/pubmed/29296952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003129
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