Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies

Monosomy 7 and del(7q) are associated with adverse features in myeloid malignancies. A 2.5-Mb commonly deleted segment (CDS) of chromosome band 7q22 is implicated as harboring a myeloid tumor suppressor gene (TSG); however, molecular analysis of candidate TSGs has not uncovered loss of function. To...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Wong, Jasmine C. Y., Zhang, Yan, Lieuw, Kenneth H., Tran, Mary T., Forgo, Erna, Weinfurtner, Kelley, Alzamora, Pilar, Kogan, Scott C., Akagi, Keiko, Wolff, Linda, Le Beau, Michelle M., Killeen, Nigel, Shannon, Kevin
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881500/
https://ncbi.nlm.nih.gov/pubmed/20233966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-232504
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki