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Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease
We report that rapamycin, an allosteric inhibitor of certain but not all actions of the key cellular kinase mammalian target of rapamycin (mTOR), protects neurons from death in both cellular and animal toxin models of Parkinson's disease (PD). This protective action appears to be attributable t...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880868/ https://ncbi.nlm.nih.gov/pubmed/20089925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3944-09.2010 |
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