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RTP801 Is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/Activation

Previously, we reported that RTP801, a stress regulated protein, is induced in multiple cellular models of Parkinson's disease (PD), in an animal model of PD and in dopaminergic neurons of PD patients. In cellular PD models, RTP801 is both sufficient and necessary for death. We further showed t...

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Detaylı Bibliyografya
Asıl Yazarlar: Malagelada, Cristina, Jin, Zong Hao, Greene, Lloyd A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865436/
https://ncbi.nlm.nih.gov/pubmed/19118169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3928-08.2008
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