CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

There is increasing evidence that neuron death in neurode-generative diseases, such as Parkinson's disease, is due to the activation of programmed cell death. However, the upstream mediators of cell death remain largely unknown. One approach to the identification of upstream mediators is to per...

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Detalhes bibliográficos
Main Authors: Silva, Robert M., Ries, Vincent, Oo, Tinmarla Frances, Yarygina, Olga, Jackson-Lewis, Vernice, Ryu, Elizabeth J., Lu, Phoebe D., Marciniak, Stefan J., Ron, David, Przedborski, Serge, Kholodilov, Nikolai, Greene, Lloyd A., Burke, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082498/
https://ncbi.nlm.nih.gov/pubmed/16135078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2005.03428.x
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