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Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors
Smad1 is a downstream effector of the BMP signaling pathway that binds regulatory DNA to execute gene expression programs leading to, for example, the maintenance of pluripotency in mice. On the contrary, the TGF-β-activated Smad3 triggers strikingly different programs such as mesodermal differentia...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879523/ https://ncbi.nlm.nih.gov/pubmed/20147459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq046 |
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