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Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA

Sox17 is a member of the SRY-related high-mobility group (HMG) of transcription factors that have been shown to direct endodermal differentiation in early mammalian development. The LAMA1 gene encoding the α-chain of laminin-1 has been reported to be directly bound and regulated by Sox17. This paper...

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Detalhes bibliográficos
Main Authors: Ng, Calista Keow Leng, Palasingam, Paaventhan, Venkatachalam, Rajakannan, Baburajendran, Nithya, Cheng, Jason, Jauch, Ralf, Kolatkar, Prasanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593696/
https://ncbi.nlm.nih.gov/pubmed/19052383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108038724
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